Progesterone, on the other hand, is made by the ovaries, placenta and adrenal glands.
This hormone is secreted by the female reproductive system to regulate the lining of the uterus.
So, both hormones play some role in pregnancy and regulating the menstrual cycle.
In healthy women, the progesterone/estradiol ratio should be between 100 and 500.
However, sometimes you can have more of one hormone than the other. Oestrogen dominance is more likely.